Gene Machine: The Lac Operon
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About
Topics
- Gene Regulation
- Genes
- Cellular Metabolism
- Cells
Description
Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.
Sample Learning Goals
- Predict the effects on lactose metabolism when the various genes and DNA control elements are mutated (added or removed).
- Predict the effects on lactose metabolism when the concentration of lactose is changed.
- Explain the roles of LacI, LacZ, and LacY in lactose regulation.
For Teachers
Teacher-Submitted Activities
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Authors | Level | Type |
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| Gene Machine: Lac Operon -an inquiry lesson |
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Trish Loeblein | UG-Intro | CQs Lab HW |
| lac Operon Simulation |
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Chris Justus | HS | CQs | |
| How do PhET simulations fit in my middle school program? |
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Sarah Borenstein | MS | Other | |
| Alignment of PhET sims with NGSS |
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Trish Loeblein | HS | Other | |
| Operon Modeling 2.0 | Bob Kuhn | HS | Guided | ||
| PhET Simulation- Lac Operon | Pj Foley | HS | Lab Discuss Demo Guided |
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| MS and HS TEK to Sim Alignment | Elyse Zimmer | MS HS |
Other | ||
| Study Guide for lac Operon Simulation | Daryle LaFleur | UG-Intro HS |
Lab HW |
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| Simulações no Ensino de Fisica | Carla Tavares | HS | Guided MC Demo Other Lab HW Discuss |
Translations
Related Simulations
Software Requirements
| Windows | Macintosh | Linux |
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Microsoft Windows XP/Vista/7 Sun Java 1.5.0_15 or later
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OS 10.5 or later Sun Java 1.5.0_19 or later
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Sun Java 1.5.0_15 or later
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Credits
| Design Team | Third-party Libraries | Thanks To |
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